Oral Myxomatous Lesions
Authors:
Dr. Sourabh Savale,
Dr. Avinash Tamgadge,
Format: Paperback | Genre : Medical Science | Other Book Detail
Format: Paperback | Genre : Medical Science | Other Book Detail
A myxoma (Latin from Greek 'muxa' is mucus) is a myxoid tumour of primitive
[1] connective tissue defined by Virchow. Rudolph Virchow coined the term "myxoma" to
describe a soft tissue tumour that histologically resembled the structure of the umbilical
cord.
Myxomas are benign, with the presence of epithelial, mesenchymal,endothelial,
myofibroblastic, and neuroendocrine proteins in immunohistochemistry suggesting
primordial pluripotent mesenchymal cells.
The five types naming intramuscular myxoma, juxta-articular myxoma, superficial
angiomyxoma, aggressive angiomyxoma and myxoid neurothekeoma are regarded as
the mainstream soft tissue myxomas. Myxomas are defined as soft tissue tumours and
have a common histologic appearance of myxoid ground material & shows a
characteristic histopathological finding due to the presence of significant amount of
[3] myxomatous connective tissue bounded by collagen fibres.
Histological criteria for the diagnosis of myxoma was proposed by Stout deeming it as a
true neoplasm of mesenchymal origin composed of undifferentiated stellate cells in a
myxoid stroma with delicate reticulin fibers.
Intraoralsoft tissue myxoma is frequently misdiagnosed and difficult to distinguish from
other tumours. It is a slow-growing, benign mesenchymal tumour that is extremely rare
among the several types of soft tissue myxoma. It can be odontogenic or nonodontogenic myxoma based on origin. Histologically they can be differentiated with the
help of haematoxylin & eosin. The presence of odontogenic epithelium is classic feature
which can be used for diagnosis & categorization.
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